About
Brilliant Minds is an NBC medical drama created and written by Michael Grassi, inspired by the celebrated case study books of neurologist Oliver Sacks -- The Man Who Mistook His Wife for a Hat and An Anthropologist on Mars. Zachary Quinto stars as Dr. Oliver Wolf, an unorthodox and empathetic neurology attending physician at the fictional Bronx General Hospital in New York City, who has the rare condition of face blindness (prosopagnosia). The cast includes Tamberla Perry, Ashleigh LaThrop, Alex MacNicoll, Aury Krebs, Spence Moore II, Teddy Sears, and Donna Murphy as the hospital's formidable chief of medicine. Each episode features a different neurological case alongside the ongoing character arcs of Dr. Wolf and his team of interns, exploring the mysteries of the human brain through compassionate storytelling. The series premiered on September 23, 2024, on NBC with a 13-episode first season. Principal photography for Season 1 took place in Toronto from April 8 through August 23, 2024. The show was renewed for a second season in May 2025, with filming beginning on July 2, 2025, at the William F. White Heritage Studio in Mississauga, Ontario, with additional shooting in Toronto, Hamilton, and select scenes filmed in the Bronx to maintain the New York setting's authenticity.
Filming Locations
2 locationsHeritage Studio
Mississauga
Season 2 with Zachary Quinto. Soundstages in Mississauga, exterior shoots in Toronto and Hamilton
Toronto
Jul 2, 2025 - Mar 6, 2026
Downtown Toronto
Various streets, Toronto
Downtown streets doubling for the Bronx and Manhattan
Toronto
Jul 2, 2025 - Mar 6, 2026
Sources
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